In fact, OTC cough and cold medicine is one of the most popular drugs that youth use to get high. According to the Monitoring the Future survey funded by the National Institute on Drug Abuse, more teens got high from OTC medicine in 2019 than from prescription opioids. DXM taken in large enough quantities is a dissociative, hallucinogenic drug much like ketamine or PCP.
It’s a dissociative, which means it disconnects conscious thought from reality. It can force the mind into a state of altered reality and dissolve the concept of self vs. others. DXM isn’t the active ingredient; it’s a prodrug for dextrorphan — which is what produces the majority of the effects of the drug. Once absorbed through the digestive tract, DXM is quickly converted to dextrorphan by the liver.
Dextromethorphan Is Effective For Which Type Of Cough?

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The Health Effects Of Long-Term Cough Syrup/DXM Use
This also depends upon whether you’re taking it as it is intended to be used or if you’re taking it for recreational purposes to try to get high. You’re likelihood of experiencing any noticeable side effects is going to be much lower if you’re taking it the way it is intended to be used. DXM and Benadryl can cause similar effects but are two different kinds of products.
Effects Of Abuse
What you’ll pay for dextromethorphan may depend on your location, the form you choose, and other factors. Find answers to some commonly asked questions about dextromethorphan. Anyone who is misusing DXM and wishes to stop should speak with a doctor, who can offer advice on the best treatment approach.
Respiratory Depression

A drug called dextromethorphan (DXM) replaced codeine in cough medicines. At very high doses, it can mimic the effects of illegal drugs like PCP and ketamine. Nonprescription cough and cold combination products, including products that contain dextromethorphan, can cause serious side effects or death in young children. Do not give these products to children younger than 4 years of age. If you give these products to children 4-11 years of age, use caution and follow the package directions carefully. Dextromethorphan (DXM) is an over-the-counter (OTC) cough suppressant found in many OTC cough medicines.
Dextromethorphan Uses

However, in higher doses, DXM can become habit-forming and addictive. Very high doses (1500 mg or higher) can easily lead to psychotic episodes and permanent mental health issues. Dextromethorphan is the only cough suppressant available as an over-the-counter drug without a prescription. Whether or not you have health insurance, cost may be a factor when you’re considering dextromethorphan.
Drug Interactions
At this point, it becomes much harder to quit using the substance. Every time you stop taking it, withdrawal symptoms start to appear — prompting you to take more of it to feel normal again. Any dose can lead to physical dangers such as heatstroke, respiratory depression (breathing that’s become too slow), or liver damage.
“Extended release” means the drug is released into your body slowly over a long period of time. The information below is from the instructions on the product labels. Taking a medication with certain vaccines, foods, and other things can affect how the medication works. If a person has concerns that someone they know is misusing DXM, they can look out for certain signs. A person may be able to help prevent their child from taking DXM by speaking with them about its dangerous effects.
- You should not use dextromethorphan for a cough with a fever, rash, or headache that will not go away.
- Some limit the amount of dextromethorphan products that can be sold.
- And see the “Questions about taking dextromethorphan” section below for information on how to take dextromethorphan.
- But if you do find evidence of abuse, it may be time for a talk with your child.
- When used recreationally, DXM has a complex pharmacological and effect profile that resembles other dissociative drugs such as PCP, ketamine, MXE, and nitrous.
The effects of DXM usually begin about 30 minutes after taking it. Peak effects are reached somewhere between 2 and 4 hours after taking it and slowly fade out over the course of 4 to 6 hours. The dose for this plateau usually begins around 1.5 mg/kg up to 2.5 mg/kg. Even if DXM is taking a while to kick in, it’s never a good idea to take a second dose of DXM.

I think I’m fine but that only says so much in the grand scheme of things so just be careful and really put some research and time into your decisions. Don’t rationalize bad behavior and like always your health is much more important than whatever this drug will give you. Much of the public concern about DXM abuse centers on teens, some 4.6%2 of whom admitted to using cough syrup recreationally in a recent study. DXM is dangerous to combine with other serotonergic substances.
Cough Suppression

To view it, please log in to confirm your age.By continuing, you also agree that use of this site constitutes acceptance of Reddit’s User Agreement and acknowledgement of our Privacy Policy. “Nicotine is not an MAOI. Tobacco consumption has a mild MAO inhibiting effect, but it’s from other compounds, not the nicotine itself.” Before this we need to highlight the difference between the 3 types of DXM.
Users can develop a tolerance as well as a psychological and physical dependence to DXM. For adults, a typical cough relief dose is 10–20 mg of DXM every 4–6 hours, using up to a maximum of 120 mg in 24 hours. Children require much smaller doses—follow the label instructions. You should not use dextromethorphan for a cough with a fever, rash, or headache that will not go away. Your pharmacist can tell you all of the ingredients in the specific dextromethorphan products they stock. Dextromethorphan may cause allergic reactions, which can be serious.